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Cannabinoid Science 101: What Is Cannabichromene?

Source: Sensi Seeds

Cannabichromene (CBC) is an abundant naturally-occurring phytocannabinoid, and is thought to be the second most abundant cannabinoid in cannabis. CBC has been shown to produce antinociceptive (painkilling) and anti-inflammatory effects in rodents, and interest is now growing in its potential to treat gastrointestinal and inflammatory disorders in humans.

Cannabichromene (CBC) is one of the better-studied phytocannabinoids, but its properties and characteristics are not widely known, even within the cannabis industry. However, as the industry develops, it is becoming more apparent that cannabichromene has great medicinal importance. Furthermore, now that many U.S. dispensaries are testing their strains for cannabinoid profile, it is becoming easier to find high-CBC strains – although interested members of the public may still need to call around reputable local dispensaries to find the right medicine.

Cannabichromene (CBC) is an abundant naturally-occurring phytocannabinoid, and is thought to be the second most abundant cannabinoid in cannabis. CBC has been shown to produce antinociceptive (painkilling) and anti-inflammatory effects in rodents, although studies on humans are needed before its true potential can be known.

Chemical Structure and Properties of CBC

Just like tetrahydrocannabinol (THC) and cannabidiol (CBD), CBC is produced via an enzymatic conversion of the precursor cannabigerol (CBG). More specifically, cannabigerolic acid (CBGA, which decarboxylates to CBG) reacts with an enzyme in the glandular trichomes of the cannabis plant to form cannabichromenic acid (CBCA), which then in turn decarboxylates to CBC.

CBC shares the same molecular formula as THC and CBD: C21H30O2. Although many cannabinoids share the same formula, the atoms within the molecule are arranged in slightly different ways. This gives the individual molecules very different chemical properties, for example THC’s famous (and apparently unique among phytocannabinoids) ability to bind to the CB1-receptor and produce a strongly psychoactive effect…

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